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Both Hp and Hx scavenge at a 1:1 stoichiometry (Tolosano et al., 2002)

References KD Tripathi Essentials of Medical Pharmacology Goodman & Gilman The Pharmacological Basis of Therapeutics Review of Pharmacology Sparsh Gupta ADA Guidelines NCBI:

The American Diabetes Association upgraded GLP-1 agonists to preferred second-line agents for patients with cardiovascular comorbidities in its 2024 Standards of Care, elevating the drug class above sulfonylureas and DPP-4 inhibitors for many clinical scenarios

Synthesis and in vitro evaluation of a peptidomimetic inhibitor targeting the Src homology 2 (SH2) domain of STAT6